SelenoDB
Release 2.0
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Gene Report for SPG00000011_2.0
Identity
GeneGlutathione peroxidase 8 (GPx8)
SpeciesHomo sapiens (Human)
DescriptionGlutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent. (NCBI)
FamilyGlutathione peroxidase
SynonymsNone
Subfamily Glutathione peroxidase 8 (GPx8)
SynonymsNone
Gene IDSPG00000011
Gene release2.0
External ID ENSG00000164294.9 (Ensembl)
Annotation
Prediction method(s)
Promoter prediction (5000bp upstream, N/A) [Report annotation error]
Curated external database annotation (GENCODE, 15) [Report annotation error]
Conceptual translation (Translate, Standard code with Sec) [Report annotation error]
OrientationForward
Structure gene structure

FeatureCol PromoterCol Coding exonCol Non coding exon (UTR)Col IntronCol SECIS
ResidueCol SecCol Cys or Other

Gene
Transcript(s) Promoter(s) Protein(s) Secis
SPT00000037_2.0SPR00000048_2.0SPP00000041_2.0N/A
SPT00000038_2.0SPR00000049_2.0SPP00000042_2.0N/A
SPT00000039_2.0SPR00000050_2.0SPP00000043_2.0N/A
Genetic
Differentiation
FST
AfricaMiddle EastEuropeCentral-South AsiaEast AsiaOceaniaAmerica
Africa0.239
Middle East0.5430.419
Europe0.4970.4510.431
Central-South Asia0.4770.4120.4130.408
East Asia0.3590.2950.3000.2820.202
Oceania0.2430.0760.1140.1200.3050.265
America0.4050.2240.2450.2380.2950.5660.412

High FST

Low FST

P-value
AfricaMiddle EastEuropeCentral-South AsiaEast AsiaOceaniaAmerica
Africa0.910
Middle East0.6820.477
Europe0.0900.0870.018
Central-South Asia0.3500.3670.0180.034
East Asia0.1110.0000.0050.0000.003
Oceania0.9300.9140.9640.9480.7550.375
America0.0970.2490.2650.1160.0020.0100.137

Low P-value

High P-value

Sequence
Sequence SEQ00000011_2.0
External ID ENSG00000164294.9 (Ensembl)
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