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Release
2.0
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Gene Report for SPG00000028_2.0
Identity
Gene
Methionine-R-sufoxide reductase 3 (SelR3)
Species
Homo sapiens
(Human)
Description
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. (
NCBI
)
Family
Selenoprotein R
Synonyms
Selenoprotein X (SelX)
Selenoprotein R (SEPR)
Subfamily
Methionine-R-sufoxide reductase 3 (SelR3)
Synonyms
Methionine-R-sulfoxide reductase 3 (MsrB3)
Gene ID
SPG00000028
Gene release
2.0
External ID
ENSG00000174099.6
(
Ensembl
)
Annotation
Prediction method(s)
Promoter prediction (5000bp upstream, N/A)
[
Report annotation error
]
Curated external database annotation (GENCODE, 15)
[
Report annotation error
]
Conceptual translation (Translate, Standard code with Sec)
[
Report annotation error
]
Orientation
Forward
Structure
Feature
Col
Promoter
Col
Coding exon
Col
Non coding exon (UTR)
Col
Intron
Col
SECIS
Residue
Col
Sec
Col
Cys or Other
Gene
Transcript(s)
Promoter(s)
Protein(s)
Secis
SPT00000086_2.0
SPR00000114_2.0
SPP00000092_2.0
N/A
SPT00000087_2.0
SPR00000115_2.0
SPP00000093_2.0
N/A
SPT00000088_2.0
SPR00000116_2.0
SPP00000094_2.0
N/A
SPT00000089_2.0
SPR00000117_2.0
SPP00000095_2.0
N/A
Genetic
Differentiation
F
ST
Africa
Middle East
Europe
Central-South Asia
East Asia
Oceania
America
Africa
0.455
Middle East
0.554
0.448
Europe
0.553
0.514
0.465
Central-South Asia
0.569
0.539
0.503
0.507
East Asia
0.392
0.373
0.392
0.330
0.330
Oceania
0.418
0.452
0.445
0.417
0.411
0.317
America
0.347
0.395
0.387
0.372
0.377
0.448
0.264
High F
ST
Low F
ST
P-value
Africa
Middle East
Europe
Central-South Asia
East Asia
Oceania
America
Africa
0.011
Middle East
0.625
0.423
Europe
0.008
0.023
0.012
Central-South Asia
0.007
0.016
0.000
0.002
East Asia
0.033
0.000
0.000
0.000
0.000
Oceania
0.300
0.050
0.054
0.049
0.193
0.333
America
0.233
0.001
0.001
0.000
0.000
0.148
0.367
Low P-value
High P-value
Sequence
Sequence
SEQ00000028_2.0
External ID
ENSG00000174099.6
(
Ensembl
)
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Species for
All
CELF1
DI
eEFSec
EIF4A3
ELAVL1
Fep15
FrnE
G6PD
GPx
LRP2
LRP8
MsrA
PSTK
RPL30
SARS2
SBP2
SCLY
SECp43
SecS
Sel15
SELENBP1
SelH
SelI
SelJ
SelK
SelL
SelM
SelN
SelO
SelP
SelR
SelS
SelT
SelU
SelV
SelW
SEPSECS
SPS
TR
TTPA
XPO1
Family
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Cite
S. Castellano, V.N. Gladyshev, R. Guigó and M.J. Berry
SelenoDB: a database of selenoprotein genes, proteins and SECIS elements
Unpublished
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