SelenoDB
Release 2.0
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Gene Report for SPG00001114_2.0
Identity
GeneThioredoxin reductase 1 (TR1)
SpeciesIctidomys tridecemlineatus (Squirrel)
DescriptionThis gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. (NCBI)
FamilyThioredoxin reductase
Synonyms Thioredoxin reductase (TrxR)
Subfamily Thioredoxin reductase 1 (TR1)
Synonyms Gene associated with retinoid-IFN-induced mortality (GRIM-12)
Thioredoxin reductase 1 (TrxR1)
Gene IDSPG00001114
Gene release2.0
External IDNone
Annotation
Prediction method(s)
Promoter prediction (5000bp upstream, N/A) [Report annotation error]
Thermodynamic pattern-based SECIS prediction (SECISearch, 3.0) [Report annotation error]
(Selenoprofiles, Ensembl 68) [Report annotation error]
Conceptual translation (Translate, Standard code with Sec) [Report annotation error]
OrientationReverse
Structure gene structure

FeatureCol PromoterCol Coding exonCol Non coding exon (UTR)Col IntronCol SECIS
ResidueCol SecCol Cys or Other

Gene
Transcript(s) Promoter(s) Protein(s) Secis
SPT00001210_2.0SPR00001275_2.0SPP00001218_2.0SPS00000560_2.0
Sequence
Sequence SEQ00001113_2.0
External IDNone
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