SelenoDB: selenoproteins database

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Release 2.0

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Variant Report for SNP00000331_2.0

Gene

Glutathione peroxidase 1 (GPx1)

Species

Homo sapiens (Human)

Transcript

SPT00000017_2.0

Variant

A (G in the Reference genome)

State

Derived (G in the Ancestral genome)

Type

Non-synonymous (GCC=A to ACC=T)

Populations

Name	Region	# Individuals	Allele Frequency
Mandenka	Africa	16	0.062
Mbuti	Africa	13	0.038
N_Bantu	Africa	11	0.045
SE_Bantu	Africa	4	0.250
Yoruba	Africa	22	0.045

Balochi	Central-South Asia	22	0.023
Kalash	Central-South Asia	19	0.158

Bedouin	Middle East	44	0.023

Genetic
Differentiation

F_ST

	Africa	Middle East	Europe	Central-South Asia	East Asia	Oceania	America
Africa	0.061
Middle East	0.096	0.007
Europe	0.073	0.001	0.000
Central-South Asia	0.069	0.024	0.016	0.032
East Asia	0.051	0.000	0.000	0.012	0.000
Oceania	0.067	0.001	0.000	0.015	0.000	0.000
America	0.054	0.001	0.000	0.013	0.000	0.000	0.000

High F_ST

Low F_ST

P-value

	Africa	Middle East	Europe	Central-South Asia	East Asia	Oceania	America
Africa	0.209
Middle East	0.144	0.331
Europe	0.028	1.000	1.000
Central-South Asia	0.024	0.800	1.000	0.300
East Asia	0.020	1.000	1.000	1.000	1.000
Oceania	0.134	0.962	1.000	0.993	1.000	0.999
America	0.236	1.000	1.000	1.000	1.000	1.000	1.000

Low P-value

High P-value

VariantID

SNP00000331

Variant release

2.0

External ID

rs6446261 (dbSNP)

Sequence

SEQ00000004_2.0

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